Oxidative Stress Biomarkers of Brain Damage
نویسندگان
چکیده
منابع مشابه
Oxidative stress and brain diseases: Biomarkers and analytical methodologies
Oxidative stress is the imbalance between production of reactive oxygen species (ROS) and ability of the biological systems to readily detoxify the reactive intermediates or to repair the resulting damage. Disturbances in the normal redox state of tissues can cause toxic effects through the production of peroxides and free radicals that damage all components of the cell including proteins, lipi...
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Oxidative/nitrosative stress, a pervasive condition of increased amounts of reactive oxygen/nitrogen species, is now recognized to be a prominent feature of many acute and chronic diseases and even of the normal aging process. However, definitive evidence for this association has often been lacking because of recognized shortcomings with biomarkers and/or methods available to assess oxidative s...
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For many years it has been assumed that moderate alcohol intake might provide health benefits to humans, while alcohol abuse generally produces some systemic complications, even when physical and mental dependence on alcohol has not developed. Many studies have focused on distinct molecules that might serve as useful early or late biomarkers in individuals that consume important amounts of alco...
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SIGNIFICANCE Oxidative stress is considered to be an important component of various diseases. A vast number of methods have been developed and used in virtually all diseases to measure the extent and nature of oxidative stress, ranging from oxidation of DNA to proteins, lipids, and free amino acids. RECENT ADVANCES An increased understanding of the biology behind diseases and redox biology ha...
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ژورنال
عنوان ژورنال: Stroke
سال: 2018
ISSN: 0039-2499,1524-4628
DOI: 10.1161/strokeaha.117.018440